�Larger trials are needful to further examine and confirm the early findings on the experimental drug abiraterone acetate rayon (CB7630). Researcher Dr. Johann de Bono, from the Institute of Cancer Research and the Royal Marsden NHS Foundation Trust in the UK, who light-emitting diode two on-going clinical trials of CB7630, said bigger studies are necessary to find out the efficaciousness of the drug.
"We believe we have made a major step frontwards in the treatment of end-stage prostate cancer patients," De Bono told BBC News. He, however, added that the phase 1 and 2 findings requisite to be confirmed in larger trials.
An unwritten and irreversible inhibitor of the enzyme CYP17 that decreases testosterone and DHT to
Thursday 4 September 2008
Monday 25 August 2008
Reading review 2008: Mystery Jets
Where and when: NME/Radio 1 stage, Saturday, 3.40pm, Reading
Dress codification: It's a slip back to the 80s - or, at least, a chanceful jumble browse from the 80s. Guitarist Will Rees is sporting guitar-shaped Elton John spectacles, a pinko suit and green Doc Martens, whereas singer Blaine wears an aqua-green sport jacket topped with a string of pearls.
Who's watching: A surprisingly laddish crowd, world Health Organization seem up for getting lairy to, er, sensitive songs about knitting babies' shoes. Also, the bulk of the site's adolescent girls ar here in full fluoro get-up. Must be those sexy aqua-green blazers.
In a nutshell: After cancelling a string of summer fete appearances, it's great to see Blaine Harrison back onstage (he'd been receiving hospital treatment for a condition relating to his spina bifida). But today is mayhap not the triumphant render we hoped for, marred as it is by terrible acoustics and a crowd world Health Organization just don't seem motivated to take part in the stately art of chucking beer around and damaging their vocal chords. Sure, everyone goes risky towards the end for Two Doors Down, only we've been taking notes and, compared to yesterday's Richter scale-registering reaction to MGMT's big hits, it's barely a rumble.
High point: Blaine's vocals sound on the verge of break down during a tender rendition of Flakes.
Low point: We tested three different locations but the well-grounded still sucked the big one.
How hard did they rock?: Not very, unless your idea of rock involves a lot of distorted basso.
More info
Friday 15 August 2008
Big Brother - Rex-mohamed Divide Deepens Over Cider Row
Relations betwixt two of Big Brother's biggest personalities have taken another step backwards, with a row over cider the up-to-the-minute incident to upset Rex and Mohamed.
In an eery parallel to superpower Russia's military actions in Georgia, super-housemate Rex ? who has twice survived eviction and now has the speed hand thanks to the presence of his girlfriend Nicole in the house ? went on the offensive.
"Where's my f***ing cider?" he asked diplomatically, on discovering that two of his cans had gone missing.
It eventually emerged, thanks to the audacious efforts of head of house Michael, that Lisa and Mohamed has snuffled down the drink after mistakenly thinking they were Darnell's. He had given permission.
Rex, non accepting this explanation, launched an immediate attack on Mohamed's character. He called him "greedy Mo" and said Mohamed should suffer realised the error of his shipway before it was excessively late.
With Rex having avoided being put up for eviction this week he holds all the bargaining chips over Mohamed, with whom he has exhausted most of his time in the house on positive terms.
But he is attracting unfavorable judgment from other housemates. Lisa told Michael at the dinner board she believes Rex should have already been voted out because of his nasty type. Michael agreed, describing Rex as a "miserable b*****d".
More info
Thursday 7 August 2008
Robbie Williams
Artist: Robbie Williams
Genre(s):
Rock: Pop-Rock
Pop
Breakbeat
Other
Rock: Electronic
Rock
Electronic
Discography:
She's Madonna
Year: 2007
Tracks: 4
The Remixes in the Mix by DJ JB
Year: 2006
Tracks: 1
The Best So Far
Year: 2006
Tracks: 14
Rudebox
Year: 2006
Tracks: 17
Lovelight (CDM)
Year: 2006
Tracks: 6
Live in Vienna
Year: 2006
Tracks: 3
Live at Berlin
Year: 2006
Tracks: 24
Kids
Year: 2006
Tracks: 3
B-Sides and Rarities Vol.3
Year: 2006
Tracks: 18
B-Sides and Rarities Vol.2
Year: 2006
Tracks: 18
Tripping CDS
Year: 2005
Tracks: 3
Intensive Care
Year: 2005
Tracks: 18
B-Sides and Rarities Vol.1
Year: 2005
Tracks: 18
This Is Me...
Year: 2004
Tracks: 17
Ego Has Landed
Year: 2004
Tracks: 14
The Love Songs
Year: 2003
Tracks: 19
Live Summer 2003
Year: 2003
Tracks: 14
Live at Knebworth
Year: 2003
Tracks: 2
Escapology
Year: 2003
Tracks: 14
Swing When You're Winning
Year: 2001
Tracks: 15
Misunderstood
Year: 2001
Tracks: 3
Sing When You're Winning
Year: 2000
Tracks: 12
The Ego Has Landed
Year: 1999
Tracks: 14
Strong
Year: 1999
Tracks: 3
She's The One...
Year: 1999
Tracks: 4
Let Me Entertain You
Year: 1998
Tracks: 5
I've Been Expecting You
Year: 1998
Tracks: 14
Angels
Year: 1998
Tracks: 4
Life Thru A Lens
Year: 1997
Tracks: 11
Greatest Hits
Year: 1996
Tracks: 19
Very Best Of
Year:
Tracks: 18
POP-collection
Year:
Tracks: 19
Live 8 London
Year:
Tracks: 4
Advertising Space (Mix)
Year:
Tracks: 8
Out of all the members of Take That, Robbie Williams never really seemed to fit proscribed in. Roguishly giving where his bandmates were but cute, Williams was tougher and sexier than the stay, which made him more classifiable. He overly fought regularly with the other members and their management, principally because he was now and again adverse to being so heavily packaged. So it didn't come as a surprise that he was the number one to leave behind the gang, departing early in the summer of 1995 to follow a solo vocation (by some accounts, he was fired from the mathematical grouping). Although he was the first taboo of the gate, it took Williams awhile to get started. For most of 1995, he attempted to boost his believability by tagging along with Oasis, hoping that Noel Gallagher would give him a duet of songs. He never did, only all of his clip with Oasis launched Williams into a human beings of wakeless partying, boozing, and drugging. Over the course of 1996, he was only if heard from in gossip columns, and every published movie indicated he had put on considerable system of weights. Occasionally, he was quoted as locution his raw music would give up lightweight dance-pop for traditional Brit-pop, simply his first single was a subvention of George Michael's "Exemption '90." Released late in 1996, the unmarried was a catastrophe, only his moment individual, 1997's "Previous Before I Die," was more in the
Friday 27 June 2008
MTV Awards to hit Los Angeles
The MTV Video Music Awards (VMAs) are coming to Los Angeles this year, it was announced today (June 23).
The infamous awards show that featured Britney Spears' "comeback" performance of 'Gimme More' last year is moving from Las Vegas to Paramount Pictures Studios in Los Angeles to celebrate its 25th anniversary.
The VMAs will air live on September 7. For the first time this year, audiences will help determine the nominees, reports the Associated Press. The nominees and performers will be announced at a later date.
"With Paramount Pictures as the ideal setting, the glamour and musical heritage of LA are sure to be catalysts for creating explosive pop culture moments that the VMAs are known for," President of MTV Networks Van Toffler said in a statement.
The last time the VMAs hit Los Angeles was 10 years ago.
--By our Los Angeles staff.
Find out more about NME.
The infamous awards show that featured Britney Spears' "comeback" performance of 'Gimme More' last year is moving from Las Vegas to Paramount Pictures Studios in Los Angeles to celebrate its 25th anniversary.
The VMAs will air live on September 7. For the first time this year, audiences will help determine the nominees, reports the Associated Press. The nominees and performers will be announced at a later date.
"With Paramount Pictures as the ideal setting, the glamour and musical heritage of LA are sure to be catalysts for creating explosive pop culture moments that the VMAs are known for," President of MTV Networks Van Toffler said in a statement.
The last time the VMAs hit Los Angeles was 10 years ago.
--By our Los Angeles staff.
Find out more about NME.
Monday 23 June 2008
Doctor Issues Apology To Tom Cruise Over Comments
Reality television doctor, Dr. Drew Pinsky, has apologized for an article set to appear in Playboy, that states Tom Cruise may have experienced "serious neglect in childhood - maybe some abuse, but mostly neglect."
Pinsky's story in next month's edition claims, "A lot of people in the public eye who behave strangely have mental illness we can learn from, and much of it is based on childhood trauma, without a doubt. Take a guy like Tom Cruise. Why would somebody be drawn into a cultish kind of environment like Scientology? To me, that's a function of a very deep emptiness and suggests serious neglect in childhood - maybe some abuse, but mostly neglect."
Crusie's lawyer, Bert Fields, was quick to criticize Pinsky's remarks issuing a statement saying, "This unqualified television performer who is obviously just looking for notoriety is so grotesquely unprofessional as to pretend to diagnose Tom and others without ever meeting them. He seems to be spewing the absurdity that all Scientologists are mentally ill."
A rep for the the host of VH1's 'Celebrity Rehab with Dr. Drew' has apologized stating, "Dr. Drew meant no harm to Mr. Cruise and apologizes if his comments were hurtful."
"Although Mr. Fields's intent is clearly to slander and discredit Dr. Drew, under no circumstances is Dr. Drew making a blanket diagnosis about Scientology nor Mr. Cruise whom he does not know," the statement continues. "Dr. Drew was simply using Mr. Cruise as an example of someone who is recognizable to help the public understand. Again, Dr. Drew meant him no harm."
NEXT: Pete Wentz Denies Twins Rumor He Started
Photo courtesy of Paramount Pictures.
Monday 16 June 2008
Heath Ledger's Joker Menaces New Dark Knight Trailer
Heath Ledger's menacing portrayal of the Joker dominates the latest trailer for the upcoming Batman movie The Dark Knight.
The stunning new clip opens with a shadowy vision of Batman soaring through the Gotham City skyline.
But it’s the Joker’s psychotic presence back on the ground that is sure to crank up the anticipation ahead of the film's July release.
"It's simple: Kill the Batman," Ledger announces by way of out-lining his plan for murderous anarchy.
"The city deserves a better class of criminal and I'm gonna give it to them," he adds.
The new trailer also features Aaron Eckhart as Gotham district attorney Harvey Dent, who becomes Batman's other legendary enemy Two-Face.
Click to view the trailer
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